Two new spermidine alkaloids, myricoidine 1 and dihydromyricoidine 2 have been isolated from clerodendrum myricoides verbenaceae and their structures established by a study of. Clerodendrum is a genus of flowering plants in the family lamiaceae. Thus, new drugs are required against drugresistant plasmodium strains. Click table headers to reorder the list by that field, and use the browser search function on windows, controlf. Clerodendrum myricoides is a plant traditionally used for treatment of rheumatism, asthma, inflammatory diseases, coughs, skin diseases, vermifuge, febrifuge. Phylogenetic relationships between clerodendrum lamiaceae. In cultivation, it is frequently known by one of its synonyms, such as clerodendrum myricoides or clerodendrum myricoides ugandense. Other reports from the literature are the disinfectant and antiinflammatory.
In cultivation, it is frequently known by one of its synonyms, such as clerodendrum myricoides or clerodendrum myricoides ugandense references. Clerodendrum ugandense, rotheca myricoides, butterfly. In summer, dainty, twotone blue flowers are a feature of this tall evergreen shrub, which is ideal for planting in the background of a shrubby border. Due to the rise of drugresistant parasites and limited therapeutic efficacy of the available drugs, there is a need to search novel antimalarial drugs from medicinal plants commonly utilized as traditional. Rotheca was revived in 1998 as a result of phylogenetic analysis of dna sequences.
Rotheca myricoides in the germplasm resources information network grin, u. Pdf an ethnobotanical study of medicinal plants used by. Antimicrobial and cytotoxicity properties of the organic solvent. Clerodendrum myricoides is a kenyan herbal plant used in management of respiratory diseases. Malaria is a devastating parasitic disease which caused around 216 million cases and 445,000 deaths worldwide in 2016. Senna occidentalis 41, 42, and clerodendrum myricoides 52, 53. This study, the second on an ongoing series, reports on the medicinal plant species used in katoro ward, bukoba district, and tries to use. Department of agriculture agricultural research service. Chromatographic separation of a methanolic extract of clerodendrum myricoides led to the isolation of myricoidine 1 whose structure was elucidated using ir, nmr and melting point. Pdf phenolic glycosides from roots of clerodendrum. In vivo antimalarial activity of crude extracts and solvent fractions of. Antiplasmodial activity of solvent fractions of methanolic. Specimen of each plant was dried, identified at aklilu lemma institute of pathobiology and national herbarium of addis ababa university.
Clerodendrum ugandense, butterfly bush, shrub, rotheca. It is currently classified in the subfamily ajugoideae, being one of several genera transferred from verbenaceae to lamiaceae in the 1990s, based on phylogenetic analysis of morphological and molecular data estimates of the number of species in clerodendrum. Pdf methanolic effect of clerodendrum myricoides root. Methanolic effect of clerodendrum myricoides root extract on blood, liver and kidney tissues of mice hayelom k 1, mekbeb a 2, eyasu m 3, wondwossen e 4, kelbesa u 5.
According to the respondents, smoking of milking and storage vessels was frequently done in order to extend the fermentation time besides its provision of good flavor. Clerodendrum myricoides is a plant traditionally used for treatment of rheumatism, asthma, inflammatory diseases, coughs, skin diseases, vermifuge, febrifuge and malaria. Evolution of antimalarial drug resistance makes the development of new drugs a necessity. The plant aloe megalacantha is indigenous to ethiopia where the sap of the leaves is traditionally used for the treatment of malaria. Pdf phenolic glycosides from roots of clerodendrum myricoides. This study was aimed at evaluating the antimalarial effect of leaf latex. Rotheca myricoides butterfly bush also a name for buddleja species is a species of flowering plant in the family lamiaceae. All structured data from the file and property namespaces is available under the creative commons cc0 license. Larvicidal activity of myricoidine from clerodendrum.
The plant has been used in ayurvedic medicine, and some ayurvedic sources refer to it by the synonym clerodendrum multiflorum in india, the plant is known as arni. This article is within the scope of wikiproject plants, a collaborative effort to improve the coverage of plants and botany on wikipedia. Here we investigate the toxicity of extracts of seven medicinal plants traditionally used to treat breast cancer in ethiopia. Rotheca myricoides is native to tropical east africa and is cultivated as an ornamental throughout the tropics. Myricoidine and dihydromyricoidine, two new macrocyclic.
Ugandense is a cultivar that features intense purplishblue flowers with showy stamens. Clerodendrum phlomidis is a species of flowering plant in the family lamiaceae. From spring through fall appear the delicate and intricate flowers, suggestive of a butterfly in flight. Clerodendrum ugandense butterfly bush an open, evergreen shrub reaching 6 to 10 feet tall by 6 feet wide with 4 inch long dark green glossy leaves. Access is allocated within two business days of purchase and lasts one year. Start this article has been rated as startclass on the projects quality scale. The paper introduces the baanashada dumarka, a somali fertility therapy carried out by a spirit medium, known locally as alaqad. Cleromyrine i, a new cyclohexapeptide from clerodendrum. Methanolic effect of clerodendrum myricoides root extract on blood, liver and kidney tissues of mice. Ethnomedicine of the kagera region, north western tanzania.
Dna studies from 1998 led to a further change to its current listing as rotheca myricoides ugandense. Pdf clerodendrum myricoides is a plant traditionally used for treatment of. Evaluation of the antiplasmodial properties of selected. Rotheca myricoides previously known as clerodendrum ugandense or the blue butterfly bush is an attractive, openstructured, evergeen shrub with arching branches that bear sprays of small flowers that resemble delicate blue butterflies. The kagera region of north western tanzania has a rich culture of traditional medicine use and practices. This cultivar was originally named clerodendrum ugandense, but was later changed to clerodendrum myricoides ugandense. Box 5484000200, nairobi, kenya b east africa national museums of kenya, p. In the 20th century, rotheca was rarely recognized as separate from clerodendrum. Pdf larvicidal activity of myricoidine from clerodendrum. Clerodendrum myricoides from the same family is found in africa and india. Antiplasmodial activity of solvent fractions of methanolic root extract of dodonaea angustifolia in plasmodium berghei infected mice.
If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks. The five plants were the ones that had the highest relative frequency of citation. Traditional medicinal plant knowledge and use by local. Mice treated with 100mgkg bwday of methanol extract showed no behavioral changes. In vivo antimalarial activities of clerodendrum myricoides.
Rotheca myricoides is a species of flowering plant in the family lamiaceae. It is also known as rotheca myricoides and clerodendrum ugandense. This page was last edited on 7 december 2016, at 17. Evaluation of the mutagenic and antimutagenic effects of south african plants.
Rotheca hirsuta, clerodendrum hirsutum, clerodendrum natalense cats whiskers clerodendrum bungei cashmere cashmir bouquet, glory bower, clerodendron clerodendrum calamitosum white butterfly bush clerodendrum heterophyllum, clerodendrum aculeatum tree of little stars, escambron, tamourette. A cyclic hexapeptide was isolated from clerodendrum myricoides. Stem of clerodendrum myricoides was used as preservative if it was matured enough. Thus, the purpose of this study was to evaluate the antiplasmodial properties of ajuga integrifolia, clerodendrum myricoides, melia azedarach, peponium vogelii and premna schimperi used by the sidama people, southern ethiopia and fraction of ajuga integrifolia. In vitro antiplasmodial and cytotoxicity activities of 14 medicinal plants from kenya beatrice n. Herein, the in vivo antimalarial activity of the plant was investigated. Clerodendrum myricoides is a kenyan herbal plant used in the. In ethiopia, malaria control has been complicated due to resistance of the parasite to the current drugs. The present study deals with the toxicological investigations of chronic treatment with methanol root extract of clerodendrum myricoides on body weight, hematological and biochemical parameters, and liver and kidney tissue sections. Enjoy unrestricted access to all content and features, including. Pdf methanolic effect of clerodendrum myricoides root extract on. The dynamic interethnic interactions of different people from the surrounding countries constitute a rich reservoir of herbal based healing practices.
The child that tiire doesnt give you, god wont give you. This might be attributed to a wide spread of drug resistant parasites. Taxonomic studies in the clerodendrum myricoides group verbenaceae. This page was last edited on 15 august 2019, at 18. The study also explores a component of the baanashada, namely, the use of tiire rotheca myricoides, or the butterfly bush.
This study was, therefore, conducted to document antimalarial plants utilized by sidama people of boricha district, sidama zone, south. Over the last two centuries the circumscription of the large, pantropical genus clerodendrum lamiaceae has changed frequently, as different authorities have added or removed taxa on the basis of various morphological characters. Myricoidine and dihydromyricoidine, two new macrocyclic spermidine alkaloids from clerodendrum myricoides. Traditional healers of the study area were selected randomly and interviewed with the help of translators to gather information on the knowledge and use of medicinal plants used as a remedy for human. Traditional medicine is widely practiced in ethiopia. This page was last edited on 29 august 2017, at 22. Rotheca myricoides syn clerodendrum ugandense gardensonline. This page was last edited on 15 september 2017, at 00. In vitro antiplasmodial and cytotoxicity activities of 14.
Though we endeavour to ensure correctness, plant info, its owners and employees, cannot accept responsibility for any errors in information or any losses suffered due to the use of information on this site. It is native to africa and widely cultivated elsewhere. The knowledge and use of medicinal plant species by traditional healers was investigated in sekoru district, jimma zone, southwestern ethiopia from december 2005 to november 2006. Methanolic effect of clerodendrum myricoides root extract on blood. Baanashada is aimed at women whose fertility issues are believed to be caused by spirits. In vivo antimalarial activities of clerodendrum myricoides, dodonea angustifolia and.
Its common names include glorybower, bagflower and bleedingheart. Important source in search of such drugs is medicinal plants. Herbal medicine preparations from medicinal plants to treat malaria are potential source of new antimalarial drug development. Anticancer activity of plant genus clerodendrum lamiaceae. With the development of molecular methods for systematic research the process of circumscribing taxa has become increasingly analytical. The objective of this study was to evaluate antiplasmodial activity of fractions and sub fractions of the ethanol extract of clerodendrum myricoides leaves using 4day suppressive test against plasmodium berghei in swiss albino mice. Historically, many of the present antimalarial drugs were discovered from plants. An ethnobotanical study of medicinal plants used by the zay people in ethiopia. Files are available under licenses specified on their description page. In vivo antimalarial activity of the 80 methanolic root. For the in vivo test, samples of ajuga integrifolia, clerodendrum myricoides, melia azedarach, peponium vogelii and premna schimperi were collected from boricha district, southern ethiopia, during one of the field trips to the area. Larvicidal activity of myricoidine from clerodendrum myricoides article pdf available in bulletin of the chemical society of ethiopia 182 december 2004 with 28 reads how we measure reads. These plants, sideroxylon oxyacanthum, zanthoxylum chalybeum, clematis simensis, clematis longicauda, dovyalis abyssinica, vernonia leopoldi, and clerodendrum myricoides, were selected based on. Journal of medicinal plants research cytotoxicity of.
Muthauraa a centre for traditional medicine and drug research, kenya medical research institute, p. Antimicrobial and cytotoxicity properties of the organic. This page was last edited on 4 september 2017, at 15. This study is focusing on a novel approach to screen a large number of medicinal plants from kenya regarding their contents and availability of selected metals potentially relevant for treatment of diabetes patients.
Malaria is among the ten top leading causes of morbidity and mortality in children under5 years. Evaluation of antimalarial activity of the leaf latex and. Methanolic effect of clerodendrum myricoides root extract. For this purpose, total levels of zinc, chromium, manganese, and copper were determined by flame atomic absorption spectrometry and inductively coupled plasma mass. The freezedried extracts of rotheca myricoides hochst. Fifteen experts from 15 different countries joined with nine experts from china in beijing on 2224 september 2015 to explore the topic of traditional medicine.
Cleromyrine i, a new cyclohexapeptide from clerodendrum myricoides. Rotheca serrata is from tropical asia and has some medicinal use there. Phenolic glycosides from roots of clerodendrum myricoides. Flowering time is officially summer through to early autu. The amino acid composition was determined by chiral chromatography. Evidencebased complementary and alternative medicine. The method used in this study is the literature study. Evaluation of the mutagenic and antimutagenic effects of. Gardenia ternifolia plant is used in ethiopian traditional medicine for the treatment of malaria and is endowed with in vitro antimalarial activity.
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